CIKS (Act1) Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
CIKS (Act1) Polyclonal Antibody 100 µg  CSA-507E $255.00
Background
NFkappaB is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkappaB associates with IkappaB proteins in the cell cytoplasm, which inhibit its activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. CIKS (connection to IKK and SAPK/Jnk) or Act1 (NFkappaB activator) associates with and activates IKK. CIKS/Act1 also activates the activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (Jnk).

Table of Abbreviations

Abbreviated Name
CIKS pAb

Conjugate

Applications
IHC, WB

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from sequence near the amino terminus of human CIKS, conjugated to KLH

Host
Rabbit

Clone Number
not applicable

PositiveControls

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Ordering Info
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