Insulin Receptor (phospho-Tyr972) Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Insulin Receptor (phospho-Tyr972) Polyclonal Antibody 100 µL  CSA-720E $295.00
Background
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Table of Abbreviations

Applications
WB

Format
Purified (Immunoaffinity)

HostSpecies
rabbit

Immunogen
Synthetic phospho-peptide derived from the sequence of human Insulin Receptor; sequence identical with mouse and rat

Species Reactivity
H, M, (R)

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

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Citations
Launch Citation Database

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