PLC gamma 1 (phospho-Tyr783) Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
PLC gamma 1 (phospho-Tyr783) Polyclonal Antibody 100 µL  CSA-550E $295.00
Background
PLCgamma-1 (Phosphoinositide-specific phospholipase C) is a 135 kDa isoenzyme belonging to the PLC family of proteins that hydrolyzes phosphatidylinositol 4,5-biphosphate to produce the second messengers IP3 and diacylglycerol (DAG). PLCgamma-1 is ubiquitously expressed and modified by phosphorylation at two key tyrosine residues, Tyr783 and Tyr771, in response to non-receptor and receptor tyrosine kinase stimulation. Tyr783 phosphorylation is required for PLCgamma-1 activation, and regulates EGF-induced association of PLCgamma-1 with Akt.

Table of Abbreviations

Abbreviated Name
PLC gamma 1 phospho-Tyr783 pAb

Conjugate

Applications
ICC, WB

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic phospho-peptide derived from the sequence of human PLC¦Ã-1

Host
Rabbit

Clone Number
not applicable

Species Reactivity
H, M, (R, B, X)

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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