eIF4E-BP1 Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
eIF4E-BP1 Polyclonal Antibody  100 µg KAP-MA110E $285.00  
eIF4E-BP1 Polyclonal Antibody  25 µg KAP-MA110C $125.00  
Background
The eukaryotic translation initiation factors (eIFs) regulate translation at the level of messenger RNA engagement by the ribosome. eIF-2alpha promotes the binding of the initiator tRNA to 40S ribosomal subunits, and is a key signaling component of the unfolded protein response (UPR). eIF-4E recruits mRNAs to the eIF4F complex through binding of their 5? N7-methylguanosine cap. eIF-4E binding proteins-1 and -2 are translational repressors, sequestering eIF-4E in conditions of low cellular demand for translation. Their dissociation from eIF-4E is regulated by phosphorylation in response to growth-promoting stimuli.

Table of Abbreviations

Abbreviated Name
eIF4E-BP1 pAb

Conjugate

Applications
EMSA, WB

Isotype
not applicable

Purification
Immunoaffinity

Immunogen
Synthetic peptide derived from the sequence of human PHAS-I, conjugated to KLH; sequence identical to rat and mouse

Host
Rabbit

Clone Number
not applicable

PositiveControls
HeLa Cell Lysate, product# LYC-HL100

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
eIF4E-BP1 Polyclonal Antibody KAP-MA110E  
eIF4E-BP1 Polyclonal Antibody KAP-MA110C  

Related Products

Product Name Catalog#
eIF2 alpha (phospho-Ser52) Polyclonal Antibody
 		KAP-CP131E
eIF4E (phospho-Ser209) Polyclonal Antibody
 		KAP-CP132E

Citations
Launch Citation Database

Ordering Info
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