Caspase-3 Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Caspase-3 Polyclonal Antibody  100 µL AAP-113E $295.00  
Caspase-3 Polyclonal Antibody  25 µL AAP-113C $145.00  
Background
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Table of Abbreviations

Applications
WB

Format
Antiserum

HostSpecies
rabbit

Immunogen
Recombinant full length human Caspase-3 protein

PositiveControls
HeLa Cell Lysate, Product# LYC-HL100

Species Reactivity
H, M, R, B, C, CH, GP, HA, MO, P, RB, Y

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Product Manual

Product Name Catalog # Manual
Caspase-3 Polyclonal Antibody AAP-113E  
Caspase-3 Polyclonal Antibody AAP-113C  

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HeLa Cell Lysate
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Citations
Launch Citation Database

Ordering Info
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