Caspase-3 Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Caspase-3 Polyclonal Antibody   50 µg AAP-113D $91.00  
Caspase-3 Polyclonal Antibody   200 µg AAP-113F $217.00  
Background

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Pricing above includes discount. Offer expires June 30, 2010, or until supplies last.

 The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Table of Abbreviations

Applications
WB

Species Reactivity
H, M, R, B, C, CH, GP, HA, MO, P, RB, Y

Conjugate

Isotype
not applicable

Purification
Protein A Affinity

Immunogen
Recombinant human Caspase-3 protein (full length)

Host
Rabbit

Clone Number
not applicable

PositiveControls
HeLa Cell Lysate, Product# LYC-HL100

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_AAP-113_LOT-04010923
CofA_AAP-113_LOT-10230603
MSDS
Spec Sheet

Product Manual

Product Name Catalog # Manual
Caspase-3 Polyclonal Antibody AAP-113D  
Caspase-3 Polyclonal Antibody AAP-113F  

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HeLa Cell Lysate
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Citations
Launch Citation Database

Ordering Info
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