Chk1 Monoclonal Antibody (DCS-310)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Chk1 Monoclonal Antibody (DCS-310) 100 µg  KAM-CC111E $255.00
Background
The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)?induced degradation of cdc25A.

Table of Abbreviations

Abbreviated Name
Chk1 mAb (DCS-310)

Conjugate

Applications
IHC, IP, WB

Isotype
IgG3

Purification
Protein A Affinity

Immunogen
Recombinant human Chk1 protein

Host
Mouse

Clone Number
DCS-310

Positive Controls
HeLa Cell Lysate, LYC-HL100

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Chk1 Monoclonal Antibody (2G1D5)
 		905-770-100
DNA Damage ELISA Kit
 		EKS-350

Citations
Launch Citation Database

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