Chk2 Monoclonal Antibody (DCS-270)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Chk2 Monoclonal Antibody (DCS-270) 100 µg  KAM-CC112E $255.00
Background
The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)?induced degradation of cdc25A.

Table of Abbreviations

Abbreviated Name
Chk2 mAb (DCS-270)

Conjugate

Applications
IHC, IP, WB

Isotype
IgG2a

Purification
Protein A Affinity

Immunogen
Recombinant human Chk2 protein

Host
Mouse

Clone Number
DCS-270

PositiveControls
HeLa Cell Lysate, LYC-HL100

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
ATM (phospho-Ser1981) Polyclonal Antibody
 		905-774-100
Chk2 (NT) Polyclonal Antibody
 		905-296
p53 R2 (NT) Polyclonal Antibody
 		905-301

Citations
Launch Citation Database

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