Neurofilament NF-M Monoclonal Antibody (3H11)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Neurofilament NF-M Monoclonal Antibody (3H11) 100 µL  NBA-140E $285.00
Background
Neuron-specific neurofilaments belong to the intermediate filament protein family, also known as 10nm filaments. As major constituents of the axonal cytoskeleton, neurofilaments contain heteropolymers of three major proteins: 200 kDa heavy molecular weight protein NF-H, 160 kDa medium molecular weight protein NF-M, and 68 kDa light molecular weight protein NF-L, with the ratio of each changing during neuronal development. All three proteins contain globular head and tail domains flanking a central alpha-helical domain. An accumulation of neurofilament proteins and/or mutations in one of the three major proteins occur during the progression of numerous neurological diseases, including ALS.

Table of Abbreviations

Applications
ICC, WB

Format
Purified (Protein A)

CloneNumber
3H11

HostSpecies
mouse

Immunogen
Recombinant rat Neurofilament NF-M protein (carboxy-terminal fragment)

Species Reactivity
H, M, R, CH

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Related Products

Product Name Catalog#
Neurofilament Monoclonal Antibody (DP5-112)
 		915-027
Neurofilament NF-H Polyclonal Antibody
 		NBA-137E

Citations
Launch Citation Database

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