eIF4E (phospho-Ser209) Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
eIF4E (phospho-Ser209) Polyclonal Antibody 100 µL  KAP-CP132E $325.00
Background
The eukaryotic translation initiation factors (eIFs) regulate translation at the level of messenger RNA engagement by the ribosome. eIF-2alpha promotes the binding of the initiator tRNA to 40S ribosomal subunits, and is a key signaling component of the unfolded protein response (UPR). eIF-4E recruits mRNAs to the eIF4F complex through binding of their 5? N7-methylguanosine cap. eIF-4E binding proteins-1 and -2 are translational repressors, sequestering eIF-4E in conditions of low cellular demand for translation. Their dissociation from eIF-4E is regulated by phosphorylation in response to growth-promoting stimuli.

Table of Abbreviations

Abbreviated Name
eIF4E phospho-Ser209 pAb

Conjugate

Applications
WB

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic phospho-peptide derived from the sequence of human eIF-4E; sequence conserved with rat, mouse and rabbit

Host
Rabbit

Clone Number
not applicable

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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