Jnk1/2 (SAPK) (phospho-Thr183/Tyr185) Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Jnk1/2 (SAPK) (phospho-Thr183/Tyr185) Polyclonal Antibody  100 µL KAP-SA011E $325.00  
Background
The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also know as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinase belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.

Table of Abbreviations

Abbreviated Name
Jnk1/2 phospho-Thr183/Tyr185 pAb

Conjugate

Applications
WB

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic phospho-peptide derived from the sequence of human Jnk1/2; sequence conserved with rat, mouse, chicken, C. elegans and Drosophila

Host
Rabbit

Clone Number
not applicable

Species Reactivity
H, R

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Jnk1/2 (SAPK) (phospho-Thr183/Tyr185) Polyclonal Antibody KAP-SA011E  

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