Caspase-3 Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Caspase-3 Polyclonal Antibody   50 µL AAS-103D $72.00  
Caspase-3 Polyclonal Antibody   200 µL AAS-103F $180.00  
Background

SAVE 40%

Pricing above includes discount. Offer expires June 30, 2010, or until supplies last.

 The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Table of Abbreviations

Applications
WB

Species Reactivity
H, M, R, B, C, CH, GP, HA, MO, P, RB, S, X

Isotype
not applicable

Clone
not applicable

Purification
None

Clone Number
not applicable

Immunogen
Synthetic peptide derived from the sequence of human Caspase-3 . The peptide sequence differs from rat by 1 a.a. and from mouse by 2 a.a.

Host
Rabbit

PositiveControls
Rat Brain Tissue Extract, LYT-RB100

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_AAS-103_LOT-10290801
MSDS
Spec Sheet

Product Manual

Product Name Catalog # Manual
Caspase-3 Polyclonal Antibody AAS-103D  
Caspase-3 Polyclonal Antibody AAS-103F  

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RAIDD Polyclonal Antibody
AAP-270

Citations
Launch Citation Database

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