DFF45/ICAD Polyclonal Antibody

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Description Size Catalog# Price Quantity  
DFF45/ICAD Polyclonal Antibody  100 µg AAP-451E $255.00  
DFF45/ICAD Polyclonal Antibody  25 µg AAP-451C $115.00  
Background
Human DNA fragmentation fragment (DFF) 45 and its mouse homologue caspase activated deoxyribonuclease (ICAD) are the inhibitors of DFF40 and CAD, respectively. DFF is composed of two subunits, DFF40/CAD and DFF45/ICAD. Cleavage of DFF45/ICAD, which is mediated by caspase-3, leads to DFF40/CAD?s activation as a nuclease. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death. DFF40 mRNA is expressed in a limited number of human tissues; pancreas, spleen, prostate, and ovary.

Table of Abbreviations

Applications
IHC, WB

Purification Method
Peptide Affinity

Host Species
rabbit

Immunogen
Synthetic peptide derived from the sequence of mouse ICAD, conjugated to KLH

Species Reactivity
M, R

Format
PBS, pH 7.2, 0.02% sodium azide

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Product Manual

Product Name Catalog # Manual
DFF45/ICAD Polyclonal Antibody AAP-451E  
DFF45/ICAD Polyclonal Antibody AAP-451C  

Related Products

Product Name Catalog#
AIF (IN) Polyclonal Antibody
 		AAP-015E
Acinus (IN) Polyclonal Antibody
 		AAP-010E
DFF40/CAD (IN) Polyclonal Antibody
 		905-201
DFF40/CAD Polyclonal Antibody
 		AAP-350
DFF45/ICAD Monoclonal Antibody (6B8)
 		AAM-382E

Citations
Launch Citation Database

Ordering Info
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