DFF40/CAD Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
DFF40/CAD Polyclonal Antibody  100 µg AAP-350E $255.00  
DFF40/CAD Polyclonal Antibody  25 µg AAP-350C $115.00  
Background
Human DNA fragmentation fragment (DFF) 45 and its mouse homologue caspase activated deoxyribonuclease (ICAD) are the inhibitors of DFF40 and CAD, respectively. DFF is composed of two subunits, DFF40/CAD and DFF45/ICAD. Cleavage of DFF45/ICAD, which is mediated by caspase-3, leads to DFF40/CAD?s activation as a nuclease. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death. DFF40 mRNA is expressed in a limited number of human tissues; pancreas, spleen, prostate, and ovary.

Table of Abbreviations

Abbreviated Name
DFF40/CAD pAb

Conjugate

Applications
IHC, WB

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from the sequence of mouse DFF40/CAD, conjugated to KLH

Host
Rabbit

Clone Number
not applicable

Species Reactivity
M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
DFF40/CAD Polyclonal Antibody AAP-350E  
DFF40/CAD Polyclonal Antibody AAP-350C  

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DFF45/ICAD Polyclonal Antibody
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Citations
Launch Citation Database

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