Bim/BOD Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Bim/BOD Polyclonal Antibody  100 µg AAP-330E $285.00  
Background
Bim/BOD is a group of three splice variants, BimEL, BimL, and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bim is a critical regulator of lymphocyte homeostasis, acts as a barrier against autoimmune disease and is necessary for the apoptotic response to certain stress signals. All isoforms of Bim contain the C-terminal Bcl-2 homology domain known as BH3. Certain apoptotic stimuli release Bim from the complex which allows it to translocate to the mitochondria and bind to Bcl-2 or its homologues, thereby promoting apoptosis.

Table of Abbreviations

Abbreviated Name
Bim/BOD pAb

Conjugate

Applications
IHC, WB

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from the sequence of human Bim/BOD, conjugated to KLH

Host
Rabbit

Clone Number
not applicable

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_AAP-330_LOT-05290801
Spec Sheet

Product Manual

Product Name Catalog # Manual
Bim/BOD Polyclonal Antibody AAP-330E  

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Citations
Launch Citation Database

Ordering Info
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