rSec6 Monoclonal Antibody (9H5)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
rSec6 Monoclonal Antibody (9H5)  200 µg VAM-SV021F $340.00  
rSec6 Monoclonal Antibody (9H5)  50 µg VAM-SV021D $160.00  
Background
rSec6 and rSec8 are rat homologs of the yeast Sec6 and Sec8 proteins that are essential for protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec8 is part of a 19.5S complex that includes Sec6 and Sec15, that also associate with the ras-like GTP binding protein Sec4. An analogous 17S complex in rat brain was found to contain rSec6 and rSec8, along with eight novel proteins with a combined molecular weight of 743 kDa. The membrane-associated rSec6/8 complex co-immunoprecipitates with syntaxin, providing evidence that this complex is involved in synaptic vesicle docking and fusion at the presynaptic terminal.

Table of Abbreviations

Abbreviated Name
rSec6 MAb (9H5)

Applications
WB

Format
Purified (Protein G)

CloneNumber
9H5

HostSpecies
mouse

Immunogen
Recombinant rat Sec6 protein

PositiveControls
Mouse Brain Tissue Extract, LYT-MB100 Rat Brain Tissue Extract, LYT-RB100

Species Reactivity
H, M, R, B, C, CH, HA, MO, P, RB, S

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS
TechSpec

Product Manual

Product Name Catalog # Manual
rSec6 Monoclonal Antibody (9H5) VAM-SV021F  
rSec6 Monoclonal Antibody (9H5) VAM-SV021D  

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