Fas Monoclonal Antibody (ZB4)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Fas Monoclonal Antibody (ZB4) 100 µg  AAM-227E $295.00
Background
Fas/APO-1/CD95 is a 36 kDa cell surface type I-membrane glycoprotein that is a member of the Tumor necrosis factor receptor (TNF-R) family, which includes TNF-R1, TNF-R2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis of Fas expressing cells. Apoptosis induced by Fas-Fas ligand interaction is inhibited by a number of cytosolic factors such as the ICE/CED3 family inhibitor CrmA, and the short and long form of FLIP.

Table of Abbreviations

Abbreviated Name
Fas mAb (ZB4)

Conjugate

Applications
Flow, WB

Isotype
IgG1

Purification
Protein A Affinity

Immunogen
Recombinant human Fas protein

Host
Mouse

Clone Number
ZB4

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_AAM-227_LOT-06180817
Spec Sheet

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Citations
Launch Citation Database

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