DFF45/ICAD Monoclonal Antibody (6B8)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
DFF45/ICAD Monoclonal Antibody (6B8) 100 µg  AAM-382E $325.00
Background
Human DNA fragmentation fragment (DFF) 45 and its mouse homologue caspase activated deoxyribonuclease (ICAD) are the inhibitors of DFF40 and CAD, respectively. DFF is composed of two subunits, DFF40/CAD and DFF45/ICAD. Cleavage of DFF45/ICAD, which is mediated by caspase-3, leads to DFF40/CAD?s activation as a nuclease. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death. DFF40 mRNA is expressed in a limited number of human tissues; pancreas, spleen, prostate, and ovary.

Table of Abbreviations

Abbreviated Name
DFF45/ICAD mAb (6B8)

Conjugate

Applications
WB

Isotype
IgG1

Purification
Protein A Affinity

Immunogen
Recombinant human DFF45 protein

Host
Mouse

Clone Number
6B8

PositiveControls
HeLa Cell Lysate, LYC-HL100

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
AIF (IN) Polyclonal Antibody
 		AAP-015E
DFF40/CAD (IN) Polyclonal Antibody
 		905-201
DFF40/CAD Polyclonal Antibody
 		AAP-350
DFF45/ICAD Polyclonal Antibody
 		AAP-451
HeLa Cell Lysate
 		LYC-HL100F

Citations
Launch Citation Database

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