Caspase-9 Monoclonal Antibody (5B4)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Caspase-9 Monoclonal Antibody (5B4) 100 µg  AAM-139E $285.00
Background
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Table of Abbreviations

Abbreviated Name
Caspase-9 mAb (5B4)

Conjugate

Applications
WB

Isotype
IgG1

Purification
Protein A Affinity

Immunogen
Recombinant human Caspase-9 protein (amino-terminal fragment)

Host
Mouse

Clone Number
5B4

PositiveControls
HeLa Cell Lysate, LYC-HL100

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_AAM-139_LOT-05060803
Spec Sheet

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Caspase-9 Monoclonal Antibody (10-1-87)
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Caspase-9 Monoclonal Antibody (2-22)
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Caspase-9 Polyclonal Antibody
 		AAP-109
Caspase-9 Polyclonal Antibody
 		AAP-149

Citations
Launch Citation Database

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