Bcl-2 Monoclonal Antibody (83-8B)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Bcl-2 Monoclonal Antibody (83-8B) 100 µg  AAM-072E $295.00
Background
The Bcl-2 family of proteins regulate the intrinsic apoptotic pathway and are characterized by the sharing of at least one of four conserved Bcl-2 Homology (BH) domains. Bcl-2 family members function as either pro- or anti-apoptotic factors, and are generally categorized into three groups based on structural homology and function. Bcl-2-like proteins (Bcl-2, Bcl-xL, Bcl-w, A1, and Mcl-1) are pro-survival. Pro-apoptotic members can be sub-divided into two groups: the multi-BH domain group, including Bax, Bak, and Bok; and the more numerous and diverse BH3-only group, which includes Bim, Bad, and Bid.

Table of Abbreviations

Abbreviated Name
Bcl-2 mAb (83-8B)

Conjugate

Applications
WB, Flow

Isotype
IgG1

Purification
Protein A Affinity

Immunogen
Recombinant rat Bcl-2 ¦Â protein

Host
Mouse

Clone Number
83-8B

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

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