Bag-1 Monoclonal Antibody (4A2)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Bag-1 Monoclonal Antibody (4A2) 100 µg  AAM-400E $295.00
Background
Bag-1 is a multifunctional Bcl-2-binding protein that lacks sequence homology with Bcl-2 and its related proteins, and functions to enhance the anti-apoptotic effects of Bcl-2. Bag-1 binds to the intracellular domain of the hepatocyte growth factor (HGF) and platelet-derived growth factor (PDGF) receptors, enhancing growth factor mediated protection from apoptosis. Bag-1 is known to modulate the chaperone activity of Hsc70/Hsp70, serving as a nucleotide exchange factor via binding to the ATPase domain of Hsc70/Hsp70. Bag-1 is known to promote cell survival through activation of the Raf-1 kinase.

Table of Abbreviations

Applications
WB

Format
Purified (Protein A)

CloneNumber
4A2

HostSpecies
mouse

Immunogen
Recombinant mouse Bag-1 protein

PositiveControls
HeLa Cell Lysate, product# LYC-HL100

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Ordering Info
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