c-FLIP Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
c-FLIP Polyclonal Antibody  100 µg AAP-440E $255.00  
c-FLIP Polyclonal Antibody  25 µg AAP-440C $115.00  
Background
The cellular FLICE-like inhibitory protein, cFLIP, is a cellular homologue of the viral protein, vFLIP. cFLIP contains two death effector domains (DEDs) and is expressed as either a short or long splice variant called cFLIPs and cFLIPL, respectively. cFLIP acts as a caspase-8 dominant negative regulator, blocking apoptosis induced by the oligimerization of the adapter protein, FADD. cFLIP interacts with FADD and caspase-8 through their respective DEDs.

Table of Abbreviations

Abbreviated Name
c-FLIP pAb

Conjugate

Applications
ICC, WB

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from the sequence of human c-FLIP; sequence conserved among all c-FLIP variants

Host
Rabbit

Clone Number
not applicable

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
c-FLIP Polyclonal Antibody AAP-440E  
c-FLIP Polyclonal Antibody AAP-440C  

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Citations
Launch Citation Database

Ordering Info
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