KDEL (Grp78, Grp94) Monoclonal Antibody (10C3)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
KDEL (Grp78, Grp94) Monoclonal Antibody (10C3)  200 µg SPA-827F $350.00  
KDEL (Grp78, Grp94) Monoclonal Antibody (10C3)  50 µg SPA-827D $150.00  
KDEL (Grp78, Grp94) Monoclonal Antibody (10C3)  1 mg SPA-827J $1,550.00  
Background
The tetrapeptide KDEL, located at the carboxy-terminal sequences of luminal proteins, is a retrieval motif essential for the precise sorting of these proteins along the secretory pathway. KDEL proteins perform essential functions in the endoplasmic reticulum (ER) related to protein folding as well as assembly. The localization of chaperones and other soluble proteins to the ER is achieved by their continuous retrieval from post-ER compartments by the KDEL receptor (Erd2p), which is a membrane protein localized in the Golgi apparatus.

Table of Abbreviations

Applications
WB

Format
Purified (Protein G)

Product Image(s): click to enlarge

CloneNumber
10C3

HostSpecies
mouse

Immunogen
A 6 residue synthetic peptide (SEKDEL) based on rat rat Grp78 (amino acid residues 649-654), conjugated to KLH1

PositiveControls
HeLa Cell Lysate, LYC-HL100

Species Reactivity
KDEL sequence in proteins

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS
TechSpec

Product Manual

Product Name Catalog # Manual
KDEL (Grp78, Grp94) Monoclonal Antibody (10C3) SPA-827F  
KDEL (Grp78, Grp94) Monoclonal Antibody (10C3) SPA-827D  
KDEL (Grp78, Grp94) Monoclonal Antibody (10C3) SPA-827J  

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Grp94 Monoclonal Antibody (9G10), PE Conjugate
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Citations
Launch Citation Database

Ordering Info
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