Crystallin, Beta Monoclonal Antibody (3.H9.2)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Crystallin, Beta Monoclonal Antibody (3.H9.2)  200 µg SPA-230F $325.00  
Crystallin, Beta Monoclonal Antibody (3.H9.2)  50 µg SPA-230D $140.00  
Background
The beta-crystallins comprise a complex group of heteropolymers which are assembled from 6 primary gene products, the acidic (betaA1, betaA2, betaA3) and the basic (betaB1, betaB2, betaB3) polypeptides. beta-crystallins generally represent the second most abundant group of proteins in the lens but their proportions and properties vary with development. In the prenatal bovine lens, beta-crystallins account for 30% of the total proteins and betaH is predominant. In the adult, the total has increased to 40% due to an increased production of the betaL species. With the exception of betaB1a and betaB1b which are found only in betaH and appear to be responsible for its aggregation, all polypeptides are found in all forms of the protein. The betaB2 polypeptide (previously called betaBp) predominates, accounting for about 50% of the total. The lack of stoichiometry in the subunit contents suggests that each of the different molecular weight populations is a mixture of aggregates with most of the major polypeptides represented. These various species appear to be in equilibrium and their proportions vary with protein concentration. It is likely that even more highly aggregated forms, are the major species in the lens.

Table of Abbreviations

Applications
WB

Format
Purified (Protein G)

CloneNumber
3.H9.2

HostSpecies
mouse

Immunogen
Native bovine beta Crystallin protein

PositiveControls
Crystallin, Beta Protein, SPP-235

Species Reactivity
B, RB

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Product Manual

Product Name Catalog # Manual
Crystallin, Beta Monoclonal Antibody (3.H9.2) SPA-230F  
Crystallin, Beta Monoclonal Antibody (3.H9.2) SPA-230D  

Related Products

Product Name Catalog#
Crystallin, Beta L Native Protein
 		SPP-236
Crystallin, Beta Native Protein
 		SPP-235

Citations
Launch Citation Database

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