Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5)

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5)   200 µg SPA-815F $345.00  
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5)   50 µg SPA-815D $165.00  
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5)   1 mg SPA-815J $1,405.00  
Background
The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Table of Abbreviations

Applications
WB

Species Reactivity
H, M, R, B, C, CH, GP, HA, MO, P, RB, S

Conjugate

Isotype
IgG2a

Purification
Protein G Affinity

Immunogen
Native hamster Hsc70 (Hsp73) protein

Host
Rat

Clone Number
1B5

Product Image(s): click to enlarge

PositiveControls
HeLa Cell Lysate (Heat Shocked), LYC-HL101 Hsc70 (Hsp73) Protein, SPP-751

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_SPA-815_LOT-03020918
MSDS

Product Manual

Product Name Catalog # Manual
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5) SPA-815F   Spec Sheet    
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5) SPA-815D   Spec Sheet    
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5) SPA-815J  

Related Products

Product Name Catalog#
Grp75 (Mortalin) Polyclonal Antibody
SPS-826
Grp75 (Mortalin) Polyclonal Antibody
SPS-827
HeLa Cell Lysate
LYC-HL100F
Hsc70 (Hsp73) (ATPase Frag.) Recombinant Bovine Protein
SPP-752
Hsc70 (Hsp73) Polyclonal Antibody
SPA-819
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5), DyLight 488
SPA-815-488
Hsc70 (Hsp73) Rat Monoclonal Antibody (1B5), PE
SPA-815PE
Hsc70 (Hsp73) Recombinant Bovine Protein
SPP-751
Hsp70 (Anti-Human IgG/A/M) ELISA
EKS-750
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5)
SPA-810
Hsp70 (Hsp72) Monoclonal Antibody (N6F3-6.140)
SPA-8136
Hsp70 (Hsp72) Polyclonal Antibody
SPA-812
Hsp70 (Hsp72) Recombinant Human Protein
NSP-555
Hsp70 (Low Endotoxin) Recombinant Human Protein
ESP-555
Hsp70 Antibody Sample Pack
PAK-020
Hsp70 ELISA Kit
EKS-700B
Rabbit anti-Rat IgG Polyclonal Antibody, HRP
SAB-200J

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134