Hsp90 (water mold) Monoclonal Antibody (AC88)

Brand: Stressgen

Print Page

Description	Size	Catalog#	Price	Quantity
Hsp90 (water mold) Monoclonal Antibody (AC88)	50 痢	SPA-830D	$165.00
Hsp90 (water mold) Monoclonal Antibody (AC88)	200 痢	SPA-830F	$345.00
Hsp90 (water mold) Monoclonal Antibody (AC88)	1 mg	SPA-830J	$1,405.00

Background

The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

Table of Abbreviations

Applications
WB

Species Reactivity
H, R, M, BA, BE, C, CH, CE, F, GP, HA, MO, MU, P, RB, S, SC, WM

Conjugate

Isotype
IgG1

Clone
AC88

Purification
Protein G Affinity

Clone Number
AC88

Immunogen
Achlya ambisexualis (water mold) Hsp90 protein

Product Image(s): click to enlarge

Host
Mouse

PositiveControls
HeLa Cell Lysate (Heat Shocked), LYC-HL101 Hsp90 Protein, SPP-770 Hsp90 Alpha Protein, SPP-776

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_SPA-830_LOT-07280615
CofA_SPA-830_LOT-B510445
CofA_SPA-830_LOT_12010801
MSDS
Spec Sheet

Product Manual

Product Name	Catalog #	Manual
Hsp90 (water mold) Monoclonal Antibody (AC88)	SPA-830D
Hsp90 (water mold) Monoclonal Antibody (AC88)	SPA-830F
Hsp90 (water mold) Monoclonal Antibody (AC88)	SPA-830J

Related Products

Product Name	Catalog#
17-AAG, Hsp90 Inhibitor	HPK-101J
17-DMAG, Hsp90 Inhibitor	HPK-118J
17-GMB-APA-GA, Hsp90 Inhibitor	HPK-119J
AHA1, Activator of Hsp90 (AHSA1) Monoclonal Antibody (1A2-A8)	H00010598-M01
AHA1, Activator of Hsp90 (AHSA1) Recombinant Protein	H00010598-P01
Geldanamycin, Hsp90 Inhibitor	HPK-102J
Grp94 Monoclonal Antibody (9G10), DyLight 488	SPA-850-488
Grp94 Monoclonal Antibody (9G10), DyLight 488	SPA-850-488D
Grp94 Monoclonal Antibody (9G10), DyLight 488	SPA-850-488F
Grp94 Monoclonal Antibody (9G10), PE	SPA-850PE
Grp94 Monoclonal Antibody (9G10), PE	SPA-850PEF
Grp94 Monoclonal Antibody (9G10), PE	SPA-850PED
Grp94 Polyclonal Antibody	SPA-851
Hsp90 (water mold) Monoclonal Antibody (AC88)	SPA-830
Hsp90 (water mold) Monoclonal Antibody (AC88)	SPA-830D
Hsp90 (water mold) Monoclonal Antibody (AC88)	SPA-830F
Hsp90 (water mold) Monoclonal Antibody (AC88)	SPA-830J
Hsp90 Antibody Sample Pack	PAK-010
Hsp90 Antibody Sample Pack with Protein Standards	PAK-011
Hsp90 Monoclonal Antibody (16F1)	SPA-835
Hsp90 Monoclonal Antibody (16F1)	SPA-835J
Hsp90 Monoclonal Antibody (16F1)	SPA-835D
Hsp90 Monoclonal Antibody (16F1)	SPA-835F
Hsp90 Monoclonal Antibody (16F1), Biotin	SPA-835B
Hsp90 Monoclonal Antibody (16F1), Biotin	SPA-835BE
Hsp90 Monoclonal Antibody (2D12)	SPA-845
Hsp90 Monoclonal Antibody (2D12)	SPA-845E
Hsp90 Monoclonal Antibody (2D12)	SPA-845D
Hsp90 Monoclonal Antibody (AC88), DyLight 488	SPA-830-488
Hsp90 Monoclonal Antibody (AC88), PE	SPA-830PE
Hsp90 Native Human Protein	SPP-770
Hsp90 Native Human Protein	SPP-770F
Hsp90 Native Human Protein	SPP-770D
Hsp90 Polyclonal Antibody	SPA-836
Hsp90 Polyclonal Antibody	SPA-836F
Hsp90 Polyclonal Antibody	SPA-836D
Hsp90 alpha ELISA Kit	EKS-895
Hsp90 alpha Monoclonal Antibody (9D2)	SPA-840
Hsp90 alpha Monoclonal Antibody (9D2)	SPA-840F
Hsp90 alpha Monoclonal Antibody (9D2)	SPA-840D
Hsp90 alpha Monoclonal Antibody (9D2)	SPA-840J
Hsp90 alpha Monoclonal Antibody (9D2), HRP	SPA-840HRP
Hsp90 alpha Monoclonal Antibody (9D2), HRP	SPA-840HRPD
Hsp90 alpha Monoclonal Antibody (9D2), HRP	SPA-840HRPF
Hsp90 alpha Polyclonal Antibody	SPS-771
Hsp90 alpha Polyclonal Antibody	SPS-771F
Hsp90 alpha Polyclonal Antibody	SPS-771D
Hsp90 alpha Polyclonal Antibody	SPS-771J
Hsp90 alpha Recombinant Human Protein	SPP-776
Hsp90 alpha Recombinant Human Protein	SPP-776D
Hsp90 alpha Recombinant Human Protein	SPP-776F
Hsp90 beta Monoclonal Antibody (K3701)	SPA-843
Hsp90 beta Monoclonal Antibody (K3701)	SPA-843D
Hsp90 beta Monoclonal Antibody (K3701)	SPA-843F
Hsp90 beta Monoclonal Antibody (K3705)	SPA-842
Hsp90 beta Monoclonal Antibody (K3705)	SPA-842D
Hsp90 beta Monoclonal Antibody (K3705)	SPA-842F
Hsp90 beta Recombinant Human Protein	SPP-777
Hsp90 beta Recombinant Human Protein	SPP-777F
Hsp90 beta Recombinant Human Protein	SPP-777D
Hsp90 pAb	SPA-846
Hsp90 pAb	SPA-846D
Hsp90 pAb	SPA-846F
UNC45 Monoclonal Antibody (AbS1)	SRA-1800
UNC45 Monoclonal Antibody (AbS1)	SRA-1800D
UNC45 Monoclonal Antibody (AbS1)	SRA-1800F

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134

Browse by

Hsp90 (water mold) Monoclonal Antibody (AC88)