Hsp70 (Hsp72) Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hsp70 (Hsp72) Polyclonal Antibody  200 µg SPA-811F $305.00  
Hsp70 (Hsp72) Polyclonal Antibody  50 µg SPA-811D $125.00  
Background
The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Table of Abbreviations

Applications
IP, WB

Format
Protein A Affinity

Product Image(s): click to enlarge

HostSpecies
rabbit

Immunogen
Synthetic peptide derived from the sequence of human Hsp70

PositiveControls
HeLa Cell Lysate (Heat Shocked), LYC-HL101 Hsp70 (Hsp72) Protein, NSP-555

Species Reactivity
H, M, R, B, C, HA, MO, P, S

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Product Manual

Product Name Catalog # Manual
Hsp70 (Hsp72) Polyclonal Antibody SPA-811F  
Hsp70 (Hsp72) Polyclonal Antibody SPA-811D  

Related Products

Product Name Catalog#
Goat anti-Mouse IgG Polyclonal Antibody, AP Conjugate
 		SAB-101J
HeLa Cell Lysate (Heat Shocked)
 		LYC-HL101F
Hsp70 (Hsp72) Active Recombinant Protein
 		NSP-555
Hsp70 ELISA Kit
 		EKS-700B
Hsp70 High Sensitivity ELISA Kit
 		EKS-715

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134