Cytochrome c Monoclonal Antibody (6H2.B4)

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Description Size Catalog# Price Quantity  
Cytochrome c Monoclonal Antibody (6H2.B4) 100 µg  905-634 $295.00
Background
Cytochrome c, which is a critical component of the electron transport chain, is a component of the functional apoptosome. Upon release from the mitochondria, cytochrome c binds to the adaptor proteins Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex. This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death.

Table of Abbreviations

Applications
EIA, IP

Format
1 mg/mL concentration in PBS with 0.1% sodium azide

CloneNumber
6H2:B4

HostSpecies
mouse

Immunogen
Native rat Cytochrome c

Isotype
mouse IgG1

PurificationMethod
Protein G

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Ordering Info
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