Serotonin Monoclonal Antibody (SPM146)

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
Serotonin Monoclonal Antibody (SPM146) 1.0 mL  905-548 $195.00
Background
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine found in the central nervous system, gastrointestinal tract, and blood with broad physiological functions in neurotransmission, gastric motility, hemostasis, and cardiovascular integrity. Seven subclasses (5-HT 1-7) of serotonin receptors have been identified, a majority of which are members of the seven transmembrane domain-containing GPCR family, and are the target of several anti-depressant drugs. The 5-HT1 subclass consists of five highly homologous receptors that couple via G(i/o) alpha subunits to inhibit adenylyl cyclase activity. 5-HT1A expression in mammals is strongest in CNS limbic pathways that control emotion, including tissue of the hippocampus, dorsal raphé, and septum.

Table of Abbreviations

Applications
IHC

Conjugate

Species Reactivity
H

Abbreviated Name
Serotonin MAb (SPM146)

Isotype
IgG1

Purification

Immunogen
5-Hydroxytryptamine hydrochloride (3-(2-aminoethyl)-5-hydroxyindole serotonin).

Host
Mouse

Clone Number
SPM146

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Ordering Info
Click here to learn more about online ordering
Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134