PIP2 (Phosphatidylinositol-4,5-bisphosphate) Monoclonal Antibody

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Description Size Catalog# Price Quantity  
PIP2 (Phosphatidylinositol-4,5-bisphosphate) Monoclonal Antibody 100 µg  915-062 $325.00
Background
Metabolism of inositol phospholipids by intracellular signaling mediators is fundamental to signal transduction in eukaryotic cells. PI-4,5-P2 (PIP2) can be synthesized by phosphorylation of PI-4-P by type I phosphatidylinositol phosphate kinase (PIP5K I), or phosphorylation of PI-5-P by type II PIPK (PIP4K II). PI-4,5-P2 regulation of cellular calcium levels involves its hydrolysis by Phospholipase C (PLC) to produce inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG), which serve as second messengers in the import of calcium via IP3-sensitive ion channels and in the activation of PKC, respectively.

Table of Abbreviations

Abbreviated Name
PIP2 Phosphatidylinositol-4,5-bisphosphate mAb

Conjugate

Isotype
IgG2b

Purification
Protein G Affinity

Immunogen
PIP2 from bovine spinal cord

Host
Mouse

Clone Number
not available

Species Reactivity
Species Independent

Applications
EIA, ICC, IF

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Mesothelin Monoclonal Antibody (SPM143)
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PIP (Phosphatidylinositol-4 monophosphate) Monoclonal Antibody
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PIP2 (Phosphatidylinositol-4,5-bisphosphate) Monoclonal Antibody
 		915-052
PLC gamma 1 (phospho-Tyr783) Polyclonal Antibody
 		905-758-100

Citations
Launch Citation Database

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