iNOS Polyclonal Antibody

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Description Size Catalog# Price Quantity  
iNOS Polyclonal Antibody  1.0 mL 905-431 $295.00  
Background
Nitric oxide (NO) is synthesized from L-arginine, oxygen, and NADPH by three known isoforms of heme-containing flavoproteins termed NO synthases (NOS I-III). Analysis of cDNA clones has identified three distinct NOS genes in mammals: neuronal (nNOS/NOS-I), endothelial (eNOS/NOS-III), and inducible (iNOS/NOS-II). eNOS and nNOS are constitutively expressed, agonist-triggered, Ca2+/calmodulin-dependent, and are inhibited by L-arginine analogues (L-NNA, L-NMMA). They are expressed in endothelium, adrenal glands, brain, and platelets. iNOS is inducible, Ca2+/calmodulin-independent, and also inhibited by NMMA and L-NNA. It is expressed in macrophages, hepatocytes, tumor cells, vascular smooth muscle and endothelial cells.

Table of Abbreviations

Abbreviated Name
iNOS pAb

Conjugate

Isotype
not applicable

Applications
IHC

Purification
Affinity Purified

Immunogen
Synthetic peptide derived from a sequence near the carboxy-terminus of mouse iNOS

Host
Rabbit

Clone Number
not applicable

Product Image(s): click to enlarge

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation

Product Manual

Product Name Catalog # Manual
iNOS Polyclonal Antibody 905-431   Spec Sheet   

Related Products

Product Name Catalog#
eNOS Polyclonal Antibody
 		905-386
iNOS Polyclonal Antibody
 		KAS-NO001E
iNOS Polyclonal Antibody
 		KAS-NO001C

Citations
Launch Citation Database

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