c-Met Polyclonal Antibody

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
c-Met Polyclonal Antibody 100 µg  905-076 $295.00
Background
Binding of Scatter factor (SF)/Hepatocyte growth factor (HGF) to the c-Met receptor tyrosine kinase (RTK) triggers receptor dimerization and phosphorylation on multiple residues within the juxtamembrane, catalytic core and cytoplasmic tail domains, thereby regulating receptor internalization, catalytic activity and multisubstrate docking. Activation of the c-Met receptor results in binding and/or phosphorylation of many intracellular signaling proteins including multiple adaptor proteins (e.g., Grb2, Shc, Cbl, Crk, Cortactin, Paxillin, and GAB1), and a variety of other signal transducers (e.g., PI 3-kinase, FAK, Src, Erk1/2, Jnk, PLC-gamma, and Stat3).

Table of Abbreviations

Abbreviated Name
c-Met pAb

Conjugate

Applications
IHC, WB

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic peptide of C -terminal Human c-Met ¦Â

Host
Rabbit

Clone Number
not applicable

Cross Reactivities
Reacts to c-Met beta chain

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Goat anti-Rabbit IgG Polyclonal Antibody, HRP
 		SAB-300
HGF/SF Monoclonal Antibody (7-2)
 		905-165
HGF/SF Monoclonal Antibody (A10)
 		905-163
MET/HGFR (phospho-Tyr1234/Tyr1235) Monoclonal Antibody (6AT1877)
 		905-696-100
c-Met (phospho-Tyr1230/Tyr1234/Tyr1235) Polyclonal Antibody
 		KAP-TK010E

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134