AIF (IN) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
AIF (IN) Polyclonal Antibody 100 µg  905-168 $295.00
Background
Apoptosis inducing factor (AIF) is a mitochondrial inter-membrane flavoprotein that is ubiquitously expressed both in normal tissues and in a variety of cancer cell lines. AIF is synthesized as a nonapoptogenic precursor in the cytoplasm and efficiently imported into the mitochondrial inter-membrane space. Mature AIF protein is normally confined to the mitochondrial inter-membrane space. In a variety of different apoptosis-inducing conditions AIF translocates through the outer mitochondrial membrane to the cytosol and to the nucleus. Extra-mitochondrial AIF induces nuclear chromatin condensation and large scale (~50kb) DNA fragmentation.

Table of Abbreviations

Abbreviated Name
AIF pAb

Conjugate

Applications
IHC, WB

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Ion Exchange

Immunogen
Synthetic peptide derived from the sequence of human AIF

Host
Rabbit

Clone Number
not applicable

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_905-168_LOT-06040818
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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