DFF40/CAD (IN) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
DFF40/CAD (IN) Polyclonal Antibody 100 µg  905-201 $255.00
Background
Human DNA fragmentation fragment (DFF) 45 and its mouse homologue caspase activated deoxyribonuclease (ICAD) are the inhibitors of DFF40 and CAD, respectively. DFF is composed of two subunits, DFF40/CAD and DFF45/ICAD. Cleavage of DFF45/ICAD, which is mediated by caspase-3, leads to DFF40/CAD?s activation as a nuclease. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death. DFF40 mRNA is expressed in a limited number of human tissues; pancreas, spleen, prostate, and ovary.

Table of Abbreviations

Abbreviated Name
DFF40/CAD pAb

Conjugate

Applications
ICC, WB

Isotype
not applicable

Purification
Affinity Purified

Immunogen
Synthetic peptide derived from the sequence of human DFF40

Host
Rabbit

Clone Number
not applicable

PositiveControls
K562 or Jurkat whole cell lysates

Species Reactivity
H, M, R

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_905-201_LOT-06240805
Spec Sheet

Related Products

Product Name Catalog#
DFF40/CAD Polyclonal Antibody
 		AAP-350
DFF45/ICAD Monoclonal Antibody (6B8)
 		AAM-382E
DFF45/ICAD Polyclonal Antibody
 		AAP-451
EndoG Polyclonal Antibody
 		905-220

Citations
Launch Citation Database

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