Bcl-2 (human total) EIA Kit

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Description Size Catalog# Price Quantity  
Bcl-2 (human total) EIA Kit 1x96 well  900-133 $525.00
Background
The Bcl-2 family of proteins regulate the intrinsic apoptotic pathway and are characterized by the sharing of at least one of four conserved Bcl-2 Homology (BH) domains. Bcl-2 family members function as either pro- or anti-apoptotic factors, and are generally categorized into three groups based on structural homology and function. Bcl-2-like proteins (Bcl-2, Bcl-xL, Bcl-w, A1, and Mcl-1) are pro-survival. Pro-apoptotic members can be sub-divided into two groups: the multi-BH domain group, including Bax, Bak, and Bok; and the more numerous and diverse BH3-only group, which includes Bim, Bad, and Bid.

Table of Abbreviations

Applications
EIA

Features

  • Most sensitive Bcl-2 immunoassay on the market
  • Kli>Thoroughly validated in cell lysates

Range
18.8-1,200 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
human Bcl-2 100%
<0.1%: Bad / Bax / Bid / Bcl-XL / cIAP1 / total JNK / pTEN / Smac/DIABLO / beta-catenin

Sample Types
Cell Lysis Buffer 2,2 million Jurkat cells per mL

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
3.8 pg/mL

Species Reactivity
H

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.

Ordering Info
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