Interleukin-1beta (human) EIA Kit

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Description Size Catalog# Price Quantity  
Interleukin-1beta (human) EIA Kit 1x96 well  900-130 $425.00
Background
The interleukin-1 (IL-1) cytokine family consists of IL-1alpha, IL-1beta, and IL-1Ralpha (receptor antagonist) which are expressed primarily by endothelial cells and activated macrophages. IL-1alpha and IL-1beta elicit pro-inflammatory cytokine production and cellular activation, and are the primary mediators of hypothalamic regulation that results in fever. IL-1alpha and IL-1beta signals are transmitted via a dual subunit IL-1 receptor composed of IL-1R1 and the IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP is vital to IL-1 signaling, as it recruits the IL-1 receptor-associated kinase (IRAK) to the receptor complex, initiating NF-kappaB pathway activation.

Table of Abbreviations

Applications
EIA

Features

  • Validated in multiple sample matrices
  • Small sample volume

Range
10.24 - 400 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
human IL-1beta 100%

Sample Types
serum, plasma, urine

Samples Per Kit
42 in duplicate per 96 well kit

Sensitivity
< 1 pg/mL

Species Reactivity
H

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout
Kit Insert
MSDS

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Citations
Launch Citation Database

Ordering Info
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