p21 (human) EIA Kit

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
p21 (human) EIA Kit 1x96 well  900-161 $525.00
Background
Progression through the cell cycle is controlled by cyclin-dependent kinases (CDKs). Human p21WAF1/CIP1 is a CDK inhibitor that was first cloned and characterized as a mediator of p53-induced growth arrest, and serves as a regulator of cell cycle progression, terminal differentiation, and apoptosis. Human p21 inhibits cyclin-CDK2 and cyclin-CDK4 complexes, regulating cell cycle progression in G1 phase. p21 expression can be induced independently of p53 by TGF-beta, tamoxifen, progesterone, nerve growth factor and apicidin. Human p21 expression has been implicated in a variety of human cancers including those of the prostate, bladder, and esophagus.

Table of Abbreviations

Applications
EIA

Features

  • Allows quantitative determination in pg/mL values
  • Results in just 3 hours

Range
15.6 - 1,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
p21 100%
<0.02%: cIAP1 / p38 / pMEK / JNK / Beta-Catenin / p300 / Smac/DIABLO

Sample Types
HeLa lysate

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
8.0 pg/mL

Species Reactivity
H

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
Assay Layout
Kit Insert (900-161)
MSDS (900-161)
Technical Bulletin (900-161)

Related Products

Product Name Catalog#
Assay Buffer 23 Concentrate, 5X, 100 mL
 		80-1601
Cyclin D1 Monoclonal Antibody (DCS6)
 		905-776-100
RIPA Cell Lysis Buffer 2, 100 mL
 		80-1284
Stop Solution 2, 10 mL
 		80-0377
TGF-beta1 EIA Kit
 		900-155
TMB Substrate, 10 mL
 		80-0350
Wash Buffer Concentrate, 100 mL
 		80-1287
p21 Recombinant Human Protein
 		908-281
p27/Kip1 (human total) EIA Kit
 		900-139
p53 EIA Kit **ON SALE**
 		900-117

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134