Complement C3a des Arg (human) EIA Kit

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
Complement C3a des Arg (human) EIA Kit  1x96 well 900-058 $470.00  
Complement C3a des Arg (human) EIA Kit  5x96 well 901-058 $1,745.00  
Background
Activation of the complement cascade is initiated by multiple pathways, including C1q binding of antigen-antibody complexes on pathogens (classical pathway), binding of serum lectin to pathogen-unique mannose residue patterns (MBL pathway), or the spontaneous hydrolysis of C3 and subsequent processing to C3 convertase (alternative pathway). C3a and C4a are two complement cleavage products of 77- and 76-amino acid residues, respectively, that are liberated into the bloodstream and processed to their more stable metabolites C3a des Arg and C4a des Arg. Although both fragments have anaphylactic properties, C3a is considered a more potent stimulator of smooth muscle cell contraction, histamine release, and inflammation than C4a. Complement activation is associated with sepsis, respiratory distress syndrome, multi-organ failure, and transplant organ rejection.

Table of Abbreviations

Applications
EIA

Features

  • Non-radioactive measurement of C3a des Arg
  • Sample prep reagents are provided

Range
0.313 - 20 ng/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
C3a des Arg 100%
C3 1.28%
C4a des Arg 0.40%
C4 0.31%
C5a des Arg 0.10%
C5 0.05%

Sample Types
EDTA plasma

Samples Per Kit
37 in duplicate per 96 well kit

Sensitivity
0.120 ng/mL

Species Reactivity
H

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
Complement C3a des Arg (human) EIA Kit 900-058   Kit Insert    MSDS   
Complement C3a des Arg (human) EIA Kit 901-058   Kit Insert    MSDS   

Related Products

Product Name Catalog#
Assay Buffer 10 Concentrate, 15 mL
 		80-0668
Assay Buffer 10 Concentrate, 27 mL
 		80-0648
Complement C4a des Arg (human) EIA Kit
 		900-059
Interleukin-6 (human) EIA Kit
 		900-033
MBL Oligomer ELISA Kit
 		KIT 029

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134